Original
papers
Zako, T., H.
Deguchi, A. Kitayama, H. Ueda and T. Nagamune. "Refolding
of firefly luciferase immobilized on agarose beads."
J.
Biochem.
127(3), 351-354
(2000) [Abstract]
Ueda, H., M. Kawahara, T. Aburatani, K. Tsumoto, K.
Todokoro, E. Suzuki, H. Nishimura, P. A. Schueler, G.
Winter, W. C. Mahoney, I. Kumagai and T. Nagamune.
"Cell-growth control by monomeric antigen; the cell surface
expression of lysozyme-specific Ig V-domains fused to
truncated Epo receptor." J. Immunol.
Methods
241(1-2), 159-170
(2000) [Abstract]
Suzuki, C., H. Ueda, W. Mahoney and T. Nagamune. "Open
Sandwich Enzyme-Linked Immunosorbent Assay for the
quantitation of small haptens." Anal.
Biochem.
286(2), 238-246
(2000) [Abstract]
Arai, R., H. Ueda, K. Tsumoto, W. C. Mahoney, I. Kumagai
and T. Nagamune. "Fluorolabeling of antibody variable
domains with green fluorescent protein variants:
Application to an energy transfer-based homogeneous
immunoassay." Protein
Eng.
13(5), 369-376
(2000) [Abstract]
Ueda, H., K. Kubota, Y. Wang, K. Tsumoto, W. Mahoney, I.
Kumagai and T. Nagamune. "Homogeneous non-competitive
immunoassay based on the energy transfer between
fluorolabeled antibody variable domains (Open sandwich
FIA)." Biotechniques
27, 738-742
(1999) [Abstract]
Suzuki, C., H. Ueda, K. Tsumoto, W. Mahoney, I. Kumagai and
T. Nagamune. "Open Sandwich ELISA with VH- / VL- alkaline
phosphatase fusion proteins." J. Immunol.
Methods
224(1-2), 171-184
(1999) [Abstract]
Ueda, H., A. Kitayama, E. Suzuki and T. Nagamune.
"Construction of catechol 2,3-dioxygenase-protein G
chimeric proteins and its application to
immunoassay." Kagaku
Kogaku Ronbunshu
24(2), 1-5 (1998)
Murayama-Kayano, E., S. Yoshimatsu, T. Kayano, T. Nishio,
H. Ueda and T. Nagamune. "Application of the random
amplified polymorphic DNA (RAPD) technique to distinguish
species of the red tide phytoplankton Chattonella
(Raaphydophyceae)." J. Ferment.
Bioeng.
85(3), 343-345
(1998)
Kim, Y. H., T. Iida, T. Fujita, S. Terada, A. Kitayama, H.
Ueda, E. V. Prochownik and E. Suzuki. "Establishment of an
apoptosis-resistant and growth-controllable cell line by
transfecting with inducible antisense c-jun gene."
Biotechnol.
Bioeng.
58(1), 65-72
(1998) [Abstract]
Arai, R., H. Ueda and T. Nagamune. "Construction of a
chimeric protein between protein G and
fluorescence-enhanced green fluorescent protein, and its
application to immunoassay." J. Ferment.
Bioeng.
86(5), 440-445
(1998)
Tsumoto, K., Y. Nishimiya, N. Kasai, H. Ueda, T. Nagamune,
K. Ogasahara, K. Yutani, K. Tokuhisa, M. Matsushima and I.
Kumagai. "Novel selection method for engineered antibodies
using the mechanism of Fv fragment stabilization in the
presence of antigen." Protein
Eng.
10(11), 1311-1318
(1997) [Abstract]
Terada, S., Y. Itoh, H. Ueda and E. Suzuki.
"Characterization and fed-batch culture of hybridoma
overexpressing apoptosis supressing gene bcl-2."
Cytotechnology
24, 135-141 (1997)
Suzuki, C., H. Ueda, E. Suzuki and T. Nagamune.
"Construction and characterization of an anti-hapten
ScFv-alkaline phosphatase chimeric protein."
J.
Biochem.
122(2), 322-329
(1997) [Abstract]
Suzuki, E., S. Terada, H. Ueda, T. Fujita, T. Komatsu, S.
Takayama and J. C. Reed. "Establishing appoptosis resistant
cell lines for improving protein productivity."
Cytotechnology
23, 55-59 (1997)
Maeda, Y., H. Ueda, J. Kazami, G. Kawano, E. Suzuki and T.
Nagamune. "Engineering of functional chimeric protein
G-Vargula luciferase." Anal.
Biochem.
249, 147-152
(1997) [Abstract]
Fukano, H., H. Ueda and E. Suzuki. "Mathematical model of
the amplification process in competitive PCR."
Seibutsu
Kogaku Kaishi
75(1), 1-8 (1997)
Fujita, T., S. Terada, K. Fukuoka, A. Kitayama, H. Ueda and
E. Suzuki. "Reinforcing apoptosis-resistance of COS and
myeloma cells by transfecting with bcl-2 gene."
Cytotechnology
25, 25-33 (1997)
Ueda, H., K. Tsumoto, K. Kubota, E. Suzuki, T. Nagamune, H.
Nishimura, P. A. Schueler, G. Winter, I. Kumagai and W. C.
Mahoney. "Open sandwich ELISA: A novel immunoassay based on
the interchain interaction of antibody variable
region." Nat.
Biotechnol.
14(12), 1714-1718
(1996) [Abstract]
Terada, S., E. Suzuki, H. Ueda and F. Makishima. "Cytokines
involving gp130 in signal transduction suppressed growth of
a mouse hybridoma cell line and enhanced its antibody
production." Cytokine
8(12), 889-894
(1996) [Abstract]
Takahashi, K., H. Ueda and E. Suzuki. "Temperature
characteristics of mammalian cell perfusion
culture." Kagaku
Kogaku Ronbunshu
22(2), 404-407
(1996)
Shindo, T., H. Ueda, F. Makishima, H. Nishimura and E.
Suzuki. "Method for obtaining mutants defective in
immunoglobulin mu transcription factors."
Biosci.
Biotech. Biochem.
60(11), 1837-1840
(1996) [Abstract]
Maeda, Y., H. Ueda, J. Kazami, G. Kawano, E. Suzuki and T.
Nagamune. "Truncation of Vargula luciferase still resulted
in retention of luminescent activity." J.
Biochem.
119(4), 601-603
(1996) [Abstract]
Maeda, Y., H. Ueda, T. Hara, J. Kazami, G. Kawano, E.
Suzuki and T. Nagamune. "Expression of a bifunctional
chimeric protein A-Vargula luciferase in mammalian
cells." Biotechniques
20(1), 116-121
(1996) [Abstract]
Kitayama, A., T. Achioku, T. Yanagawa, K. Kanou, M.
Kikuchi, H. Ueda, E. Suzuki, H. Nishimura, T. Nagamune and
Y. Kawakami. "Cloning and characterization of extradiol
aromatic ring-cleavage dioxygenases of Pseudomonas
aeruginosa JI104." J. Ferment.
Bioeng.
82(3), 217-223
(1996)
Fujita, T., S. Terada, H. Ueda and E. Suzuki.
"Overexpression of Bcl-2 improved survival of COS-1 cells
and enhanced transient protein production."
J. Ferment.
Bioeng.
82(6), 589-591
(1996)
Ueda, H., M. Nakanishi, E. Suzuki and T. Nagamune.
"Enhancement of mutation frequency with nucleotide
triphosphate analogs in PCR random mutagenesis."
J. Ferment.
Bioeng.
79(3), 303-305
(1995)
Shindo, T., H. Ueda, E. Suzuki and H. Nishimura. "A
catechol 2,3-dioxygenase gene as a reporter."
Biosci.
Biotech. Biochem.
59(2), 314-315
(1995) [Abstract]
Kohara, Y., H. Ueda and E. Suzuki. "Enhanced settling of
mammalian cells in tanks with inclined plates / simulation
by fluid mechanical model and experiment."
J. Chem.
Eng. Japan
28(6), 703-707
(1995)
Itoh, Y., H. Ueda and E. Suzuki. "Over-expression of bcl-2,
apoptosis suppressing gene, prolonged viable culture period
of hybridoma and enhanced antibody production."
Biotech.
Bioeng.
48, 118-122 (1995)
Takahashi, K., S. Terada, H. Ueda, F. Makishima and E.
Suzuki. "Growth-rate supression of cultured mammalian cells
enhances protein productivity." Cytotechnol.
15, 57-64 (1994)
Ueda, H., M. Kikuchi, S. Yagi and H. Nishimura. "Antigen
responsive antibody-receptor kinase chimera."
Bio/technol.
10(4), 430-433
(1992) [Abstract]
Shindo, T., H. Ueda, F. Makishima, E. Suzuki and H.
Nishimura. "Efficient selection of mu(m)-mutants from
mu(m)-expressing myeloma cells by treatment with ricin
A-conjugated anti-mu antibody." Somat. Cell
Molec. Genet.
18(6), 553-558
(1992) [Abstract]
Ueda, H., M. Kikuchi, A. Hasegawa, S. Yagi and H.
Nishimura. "Construction of hybrid protein combining
immunoglobulin and epidermal growth factor receptor and its
expression on the myeloma cell membrane."
Kagaku
Kogaku Ronbunshu
17(3), 547-552
(1991)
Reviews
& Book chapters
長棟輝行,
上田宏.
"抗原抗体反応によりスイッチ可能な人工受容体発現細胞の開発."
ファルマシア 36(6), 474-478
(2000)
長棟輝行
and
上田宏.
"抗体Fvとサイトカイン受容体のキメラを発現する細胞-抗原による増殖促進."
バイオサイエンスとインダストリー 58(7), 465-470 (2000)
新井亮一,
上田宏,
長棟輝行 (2000).
分子間相互作用解析.
実験医学別冊ポストゲノム時代の実験講座 3,GFPとバイオイメージング.
宮脇敦史,
羊土社: 207-214.
長棟輝行,
河原正浩,
油谷隆秀,
上田宏.
"細胞表層工学を用いた動物細胞の育種."
生物工学会誌 77(6), 510-513
(1999)
上田宏
(1999).
バイオハザード.
化学実験の安全指針(第4版).
日本化学会編,
丸善.
上田宏.
"キメラ抗体から新規免疫測定法まで."
化学工学 (1999)
上田宏,
長棟輝行,
津本浩平,
熊谷泉.
"新たな免疫測定法."
遺伝子医学 3(1), 170-175
(1999)
長棟輝行,
前田百美,
鈴木栄二,
上田宏.
"抗体結合能を持つキメラ発光酵素の創製と免疫測定系への応用."
J Grad Sch Fac Eng Univ Tokyo A-34, 92-93 (1996)
上田宏,
長棟輝行,
津本浩平,
熊谷泉.
"抗体の分子内相互作用を利用した新しい免疫測定法."
ケミカル・エンジニヤリング 41(11),
42-46 (1996)
長棟輝行,
上田宏.
"キメラ蛋白質の創製とその工学的応用."
酵素工学ニュース(34), 15-21
(1995)
上田宏.
"キメラ抗体を用いたバイオセンサーに関する研究."
化学工学 59(6), 382-383
(1995)
西村肇,
菊地昌子,
上田宏.
"抗原結合により蛋白質リン酸化活性の変化する免疫センサー蛋白質(人工受容体)の創作."
J. Fac. Eng., Univ. Tokyo A-29, 58-59 (1991)