論文・著書:2006-7

74. Sugimura, Y., Ueda, H., Maki, M., Hitomi, K. "Novel site-specific immobilization of functional protein using a preferred substrate sequence for transglutaminase 2", J. Biotechnol., 131 (2), 121-127 (2007) [Abstract]

73. Lim, S.-L., Ichinose, H., Shinoda, T. and Ueda, H. "Noncompetitive detection of low molecular weight peptides by open sandwich immunoassay" Anal. Chem., 79 (16), 6193-6200 (2007) [Abstract] [PDF]

72. T. Suzuki, Y. Munakata, K. Morita, T. Shinoda, and H. Ueda "Sensitive detection of estrogenic mycotoxin zearalenone by open sandwich immunoassay" Anal. Sci. 23, 65-70 (2007) [Abstract] [PDF]

71. M. Kawahara M., H. Ueda, K. Tsumoto, I. Kumagai, T. Nagamune, "Mimicry of erythropoietin and interleukin-6 signaling by an antibody/cytokine receptor chimera in murine myeloid 32D cells" J. Biochem., 141, 563-571 (2007) [Abstract]

70. M. Kawahara, T. Inoue, X. Ren, T. Sogo, H. Yamada, M. Katoh, H. Ueda, M. Oshimura, and T. Nagamune "Antigen-mediated growth control of hybridoma cells via a human artificial chromosome" Biochim. Biophys. Acta 1770 (2) 206-212 (2007) [Abstract]

69. Ohiro, Y., Ueda, H., Shibata, N. and Nagamune, T. "Enhanced fluorescence resonance energy transfer immunoassay with improved sensitivity based on the Fab'-based immunoconjugates" Anal. Biochem. 360 (2), 266-272 (2007) [Abstract]

68. Yoshiyuki Sasajima, Takahide Aburatani, Kenzo Sakamoto and Hiroshi Ueda "Detection of protein tyrosine phosphorylation by Open Sandwich fluoroimmunoassay" Biotechnol. Prog. 22, 968-973 (2006) [Abstract]

67. Kenji Masuda, Kenzo Sakamoto, Miki Kojima, Takahide Aburatani, Takuya Ueda, and Hiroshi Ueda "The role of interface framework residues in determining antibody VH/VL interaction strength and antigen binding affinity" FEBS J. 273, 2184-2194 (2006) [Abstract]

66. Kawahara, M., Ogo, Y., Tsumoto, K., Kumagai, I., Ueda, H. and Nagamune, T. “Growth control of hybridoma cells with an artificially induced EpoR-gp130 heterodimer” Cytotechnol. 52, 171-179 (2006). [Abstract]

65.
Hidetoshi Yamada, Atsushi Kunisato, Masahiro Kawahara, Candice G. T. Tahimic, Xianying Ren, Hiroshi Ueda, Teruyuki Nagamune, Motonobu Katoh, Toshiaki Inoue, Mitsuo Nishikawa, and Mitsuo Oshimura "Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome" J. Hum. Genet. 51, 147-150 (2006) [Abstract]


総説・著書

上田 宏 "組換えタンパク質を用いた低分子センサ” Chemical Sensors 23(1) 9-15 (2007) [Abstract]

上田 宏
"オープンサンドイッチ免疫測定法による低分子の高感度非競合的測定" 薬学雑誌 127(1) 71-80 (2007) [Abstract] [PDF]

上田 宏 "オープンサンドイッチイムノアッセイによる非競合的な低分子分析" 臨床化学
36(2) 116-124 (2007)

河原正浩,十河孝浩,上田宏,長棟輝行 "膜タンパク質の改変による細胞応答の制御" 高分子 56(10) 828-830 (2007)

上田 "抗体可変領域のタンパク質間相互作用を利用した高感度な低分子分析" 生体の科学 58(5) 370-373 (2007)

上田 宏 (共著) "ナノバイオ大事典" 山根恒夫他監修,テクノシステム(東京), 2007.

河原正浩,上田宏,長棟輝行
"動物細胞での抗体選択・生産一貫システムの開発" 抗体医薬の最前線 pp. 26-34CMC出版(東京),2007

K. Yoshitake, S. Waki, and H. Ueda "Dimerization-based homogeneous fluorosensor proteins for the detection of specific dsDNA" Nucl. Acids Symp. Ser. 51, 307-308 (2007)

S. Waki, K. Yoshitake, R. Iwasaki, and H. Ueda "Fluorosensor proteins to detect specific DNA sequences in living bacteria "
Nucl. Acids Symp. Ser. 51, 121-122 (2007)

上田 宏(共著)第5版 実験化学講座 30 化学物質の安全管理,日本化学会編,丸善(東京)2006.

上田宏, 河原正浩, 長棟輝行. "細胞表面受容体工学の最近の進歩" バイオサイエンスとインダストリー 64(2), 18-23 (2006)

K. Tanaka, M. Kawahara, H. Ueda and T. Nagamune "Promoting non-hematopoietic cell proliferation by chimeric receptors", presented at the The 9th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), Kyoto, 2006 (eds. K. Ikura, M. Nagao, A. Ichikawa, K. Teruya & S. Shirahata) 15, 9-16 (Springer).

T. Sogo, M. Kawahara, H. Ueda and T. Nagamune "Selective expansion of genetically modified t cells using a chimeric IL-2 receptor for cancer therapy", presented at the The 9th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), Kyoto, 2006 (eds. K. Ikura, M. Nagao, A. Ichikawa, K. Teruya & S. Shirahata)
15, 93-100 (Springer).

W. Liu, M. Kawahara, H. Ueda and T. Nagamune "Construction of a fluoresceinresponsive chimeric receptor with strict ligand dependency and analysis of the role of erythropoietin receptor domains in signal transduction", presented at the The 9th Annual and International Meeting of the Japanese Association for Animal Cell Technology (JAACT), Kyoto, 2006 (eds. K. Ikura, M. Nagao, A. Ichikawa, K. Teruya & S. Shirahata)
15, 197-204 (Springer).


招待講演

Y. Wu, S.-L. Lim, H. Takahashi, M. Ihara, K. Sato, K. Shimura, T. Shinoda, T. Kitamori and H. Ueda "Integrating Open Sandwich Immunoassay with Nanotechs for Rapid Detection of Small Molecules" Swiss-Japan Symposium on Nanobio 2007, Takeda Frontier Science Hall, The Univ. Tokyo (10/11, 2007).

上田 宏 ”オープンサンドイッチ免疫測定法による低分子の高感度非競合的測定” 日本薬学会第126年会シンポジウムS23-3 (3/29, 2006).

上田 宏 オープンサンドイッチ免疫測定法による低分子の高感度非競合的検出” 第6回日本蛋白質科学会年会ワークショップ (4/25, 2006).

Hiroshi Ueda "Open Sandwich Immunoassay as a general detection principle for low molecular-weight antigens" Antibody Engineering Conference, a satellite meeting of 20th IUBMB International Congress of Biochemistry and Molecular Biology, 16-17, June, 2006, Kagoshima.

Hiroshi Ueda "Open Sandwich Immunoassay: A novel immunoassay that can noncompetitively detect many low-molecular weight antigens" Seminar at Department of Molecular Biology,
Aarhus University, Denmark, 17, August, 2006.

上田 宏 "オープンサンドイッチ原理による各種生体関連分子の非競合検出とその応用” 高分子学会 バイオ・高分子研究会 (9/23, 2006).